The ABI status of ELF hash tables

That won't help with even the most basic cheats like aimbots (where the player's inputs follow all the normal rules and are processed perfectly legitimately, but they don't come directly from the player's hand) or wall hacks (where players can see through walls, detecting enemies who ought to be hard to see).

You need to either lock down the client hardware so thoroughly that you can be certain it's only running the software provided by the game developer (as with consoles), or engage in an endless arms race of updating detection for cheats which are then updated to circumvent that detection. Game developers will never completely win, but in practice they usually do a good enough job to stop the game being made unplayable by a flood of cheaters. They'd find it much harder if they freely shared their detection algorithms with the cheat developers.

(You can also limit yourself to developing games where players don't gain an unfair advantage by cheating, but a lot of people enjoy competitive PvP action games and it'd be a shame to rule them out.)