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The Internet of scary things

The Internet of scary things

Posted Feb 9, 2017 17:13 UTC (Thu) by sfeam (subscriber, #2841)
In reply to: The Internet of scary things by Wol
Parent article: The Internet of scary things

That turns out not to be the case, although it was bruited about as a rationalization for many years. There are two stereomeric states of thalidomide that can be separated in the laboratory, but they interconvert in vivo. So the biological effect of both forms come out the same. The underlying point remains the same - speeding up the approval process has risks as well as rewards.


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The Internet of scary things

Posted Feb 11, 2017 19:59 UTC (Sat) by ssokolow (guest, #94568) [Link]

Here's a citation for that, in case anyone is interested:

Thalidomide. The role of water in the mechanism of its aqueous racemisation.
0000-0002-8635-8390
http://www.ch.imperial.ac.uk/rzepa/blog/?p=8246


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