If you mean that it's better to program directly against the Xen hypervisor or some other exokernel, instead of using Linux at all, then Mirage is certainly an argument for doing that. (Also loving it myself because it's written largely in OCaml ...)
But the at some point I just know that my program is going to want to write to a file or ask the user a question, and then having Linux around and improving its support for low-level ops starts to look like a better long term option.
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