Indeed; it's a matter aligning your needs with the goals of the distribution. RHEL and CentOS with my own and Dag/RPMforge add-ons, keeps me pretty well for servers and the latest Fedora for workstations or development/preview servers.
I should note, too, that people running Red Hat 7.3 and 9 should be able to migrate fairly painlessly to RHEL/CentOS versions 2 or 3, respectively.
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