I do data scientific data visualization as a dayjob. gnome3 worksforme. Then again fvwm2 and CDE workforme as well as environments under which to perform scientific data visualization...as generally speaking the environment doesn't really matter. If your using python or C or IDL or matlab or whatever the hell your domain specific science analysis tools are written in.. the usability of the science tools themselves are orders of magnitude less advanced than any operating enviroment you could possible pick.
Now whether or not my scientific simulation, coding and visualization work is "real work" or not is certainly open for debate. And I frankly I question whether most "science" is "real work" and not just people "goofing off." But real or imagined, whatever work I do for my dayjob I do it in a gnome3 environment now, and its not getting in my way for that work afaict.