Other than possibly your very first job where they _may_ ask you how you did in school. No employer cares what grades you got in school.
The only thing that matters is "did you graduate".
If you were the top of your class, you get a slight benefit, but only if it's a large, known school, so that's about 1 person in 100,000 or so. For everyone else, it doesn't matter if you graduate with a A+ average, or with a C- average, the diploma is the same.