"The crowd could be stuck there all night if they don't leave the owner's office now."
Presumably the owner is known to be male or female anyway, but a 3-second look at that sentence told me how to rephrase it in any event. It does get easier once you start writing for neutrality on a regular basis.
It's even a plural "they" in this case :)
I've mentioned it else-thread, but Miller and Swift's "Handbook of Nonsexist Writing" is really a fantastic resource on the topic. I refer to it on at least a weekly basis.
The one word I haven't found a decent neutral version for is "handyman". "Fixer" just doesn't have the same flavour to it, and "repair person" is just meh.