Linux drivers

Ya. 

64Studio seems very good. 

The old DeMuDi distro from the Agnula project helped out tremendously to make things easier to
use. They put a lot of effort in packaging software and documenting things. I figure this is
why most audio processing applications and such are in Debian proper nowadays and is now be
re-incorporated into things like Studio64 and Ubuntu Studio. 

64Studio is probably the most mature things you can use as far as this sort of thing goes.
It's totally open source and compatible with Debian. It's also commercially oriented with
options for paid support and that happy stuff.

The cool thing is that they are seeming to gain some hardware vendor support. It started off
with Lionstrac's range of audio workstations and it looks like they picked up on a couple of
other vendors.
http://64studio.com/oem_products
http://eracks.com/products/Quiet%20Systems/config?sku=STUDIO